Why would you want multi-level STI? When you're using multiple inheritance (class_c inherits from class_b and class_b inherits from class_a) and you want that relationship maintained through ActiveRecord; that's when.
Take the following three classes for example:
/app/model/a/class_b.rb (yes, I mean dir 'a'. class_b.rb is a peer of class_a.rb)
class A::B < A
class A::B::C < A::B
Notice the explicit class hierarchy notation. Without this, I can't get the multi-level relationship maintained through STI.
From here, you can merrily create the class through ActiveRecord, assuming you have an existing table for the base class (which includes the 'type' column (where AR stashes the class hierarchy/name information for subsequent instanciations), and use all the methods.
c = A.first
c.method_a => 'a'
c.method_b => 'b'
c.method_c => 'c'